5PB4
human factor VIIa in complex with 1-[[3-[5-hydroxy-3-methyl-4-(1H-pyrrolo[3,2-c]pyridin-2-yl)pyrazol-1-yl]phenyl]methyl]-3-phenylurea at 2.43A
Summary for 5PB4
Entry DOI | 10.2210/pdb5pb4/pdb |
Group deposition | Crystal Structure of a Factor VIIa complex (G_1002016) |
Descriptor | Coagulation factor VII light chain, Coagulation factor VII heavy chain, GLYCEROL, ... (8 entities in total) |
Functional Keywords | glycoprotein, hydrolase, serine protease, plasma, blood coagulation factor, protein inhibitor complex, calcium-binding, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (Human) More |
Cellular location | Secreted: P08709 P08709 |
Total number of polymer chains | 2 |
Total formula weight | 35917.88 |
Authors | Stihle, M.,Mayweg, A.,Roever, S.,Rudolph, M.G. (deposition date: 2016-11-16, release date: 2017-06-21, Last modification date: 2024-04-03) |
Primary citation | Mayweg, A.,Roever, S.,Rudolph, M.G. Crystal Structure of a Factor VIIa complex To be published, |
Experimental method | X-RAY DIFFRACTION (2.43 Å) |
Structure validation
Download full validation report