5OAY
M. tuberculosis [4Fe-4S] protein WhiB1 is a four-helix bundle that forms a NO-sensitive complex with sigmaA and regulates the major virulence factor ESX-1
Summary for 5OAY
Entry DOI | 10.2210/pdb5oay/pdb |
NMR Information | BMRB: 34153 |
Descriptor | Transcriptional regulator WhiB1, IRON/SULFUR CLUSTER (2 entities in total) |
Functional Keywords | nitric oxide, sigmaa, iron-sulfur, tuberculosis, wbl protein, signaling protein |
Biological source | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) |
Cellular location | Cytoplasm : P9WF43 |
Total number of polymer chains | 1 |
Total formula weight | 10735.32 |
Authors | Williamson, M.P.,Green, J.,Hounslow, A.M. (deposition date: 2017-06-25, release date: 2018-01-03, Last modification date: 2024-05-15) |
Primary citation | Kudhair, B.K.,Hounslow, A.M.,Rolfe, M.D.,Crack, J.C.,Hunt, D.M.,Buxton, R.S.,Smith, L.J.,Le Brun, N.E.,Williamson, M.P.,Green, J. Structure of a Wbl protein and implications for NO sensing by M. tuberculosis. Nat Commun, 8:2280-2280, 2017 Cited by PubMed: 29273788DOI: 10.1038/s41467-017-02418-y PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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