5NF9

Structure of Galectin-3 CRD in complex with compound 2

Summary for 5NF9

• Entry DOI: 10.2210/pdb5nf9/pdb
• Related: 5NF7
• Descriptor: Galectin-3, ~{N}-[(2~{R},3~{R},4~{R},5~{S},6~{R})-2-acetamido-6-(hydroxymethyl)-5-[(2~{S},3~{R},4~{S},5~{R},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-4-oxidanyl-oxan-3-yl]-3-methoxy-benzamide (3 entities in total)
• Functional Keywords: galectin-3 crd, cation-pi interactions, sugar binding protein
• Biological source: Homo sapiens (Human)
• Cellular location: Cytoplasm: P17931
• Total number of polymer chains: 1
• Total formula weight: 16975.34

Authors

Ronin, C.,Atmanene, C.,Gautier, F.M.,Djedaini Pilard, F.,Teletchea, S.,Ciesielski, F.,Vivat Hannah, V.,Grandjean, C. (deposition date: 2017-03-13, release date: 2017-06-21, Last modification date: 2024-01-17)

• Primary citation: Atmanene, C.,Ronin, C.,Teletchea, S.,Gautier, F.M.,Djedaini-Pilard, F.,Ciesielski, F.,Vivat, V.,Grandjean, C.; Biophysical and structural characterization of mono/di-arylated lactosamine derivatives interaction with human galectin-3.; Biochem. Biophys. Res. Commun., 489:281-286, 2017; PubMed: 28554839; DOI: 10.1016/j.bbrc.2017.05.150

Experimental method

X-RAY DIFFRACTION (1.87 Å)