5N5C
NMR solution structure of the TSL2 RNA hairpin
Summary for 5N5C
Entry DOI | 10.2210/pdb5n5c/pdb |
NMR Information | BMRB: 34100 |
Descriptor | RNA (19-MER) (1 entity in total) |
Functional Keywords | terminal stem-loop 2 survival motor neuron, rna |
Biological source | Homo sapiens |
Total number of polymer chains | 1 |
Total formula weight | 6048.63 |
Authors | Garcia-Lopez, A.,Wacker, A.,Tessaro, F.,Jonker, H.R.A.,Richter, C.,Comte, A.,Berntenis, N.,Schmucki, R.,Hatje, K.,Sciarra, D.,Konieczny, P.,Fournet, G.,Faustino, I.,Orozco, M.,Artero, R.,Goekjian, P.,Metzger, F.,Ebeling, M.,Joseph, B.,Schwalbe, H.,Scapozza, L. (deposition date: 2017-02-13, release date: 2018-03-14, Last modification date: 2024-06-19) |
Primary citation | Garcia-Lopez, A.,Tessaro, F.,Jonker, H.R.A.,Wacker, A.,Richter, C.,Comte, A.,Berntenis, N.,Schmucki, R.,Hatje, K.,Petermann, O.,Chiriano, G.,Perozzo, R.,Sciarra, D.,Konieczny, P.,Faustino, I.,Fournet, G.,Orozco, M.,Artero, R.,Metzger, F.,Ebeling, M.,Goekjian, P.,Joseph, B.,Schwalbe, H.,Scapozza, L. Targeting RNA structure in SMN2 reverses spinal muscular atrophy molecular phenotypes. Nat Commun, 9:2032-2032, 2018 Cited by PubMed: 29795225DOI: 10.1038/s41467-018-04110-1 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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