5N0Z
hPAD4 crystal complex with AFM-41a
Summary for 5N0Z
Entry DOI | 10.2210/pdb5n0z/pdb |
Related | 5N0M 5N0Y |
Descriptor | Protein-arginine deiminase type-4, SULFATE ION, CALCIUM ION, ... (5 entities in total) |
Functional Keywords | hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (Human) |
Cellular location | Cytoplasm: Q9UM07 |
Total number of polymer chains | 1 |
Total formula weight | 75704.82 |
Authors | Beaumont, E.,Kerry, P.,Thompson, P.,Muth, A.,Subramanian, V.,Nagar, M.,Srinath, H.,Clancy, K.,Parelkar, S. (deposition date: 2017-02-03, release date: 2017-05-24) |
Primary citation | Muth, A.,Subramanian, V.,Beaumont, E.,Nagar, M.,Kerry, P.,McEwan, P.,Srinath, H.,Clancy, K.,Parelkar, S.,Thompson, P.R. Development of a Selective Inhibitor of Protein Arginine Deiminase 2. J. Med. Chem., 60:3198-3211, 2017 Cited by PubMed: 28328217DOI: 10.1021/acs.jmedchem.7b00274 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.52 Å) |
Structure validation
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