5MHS

T1L reovirus sigma1 complexed with 5C6 Fab fragments

Summary for 5MHS

• Entry DOI: 10.2210/pdb5mhs/pdb
• Descriptor: Outer capsid protein sigma-1, 5C6 Fab light chain, 5C6 Fab heavy chain (3 entities in total)
• Functional Keywords: reovirus sigma1, virus antibody complex, neutralization, viral protein, immune system
• Biological source: Reovirus type 1 (strain Lang); More
• Cellular location: Virion : P04506
• Total number of polymer chains: 9
• Total formula weight: 200734.94

Authors

Stehle, T.,Dietrich, M.H. (deposition date: 2016-11-25, release date: 2016-12-21, Last modification date: 2024-01-17)

• Primary citation: Dietrich, M.H.,Ogden, K.M.,Katen, S.P.,Reiss, K.,Sutherland, D.M.,Carnahan, R.H.,Goff, M.,Cooper, T.,Dermody, T.S.,Stehle, T.; Structural Insights into Reovirus sigma 1 Interactions with Two Neutralizing Antibodies.; J. Virol., 91:-, 2017; PubMed: 27928010; DOI: 10.1128/JVI.01621-16

Experimental method

X-RAY DIFFRACTION (3.7 Å)