5M8P
Crystal structure of human tyrosinase related protein 1 in complex with tyrosine
Summary for 5M8P
Entry DOI | 10.2210/pdb5m8p/pdb |
Descriptor | 5,6-dihydroxyindole-2-carboxylic acid oxidase, 2-acetamido-2-deoxy-beta-D-glucopyranose, TYROSINE, ... (14 entities in total) |
Functional Keywords | human tyrosinase related protein 1, melanin biosynthesis, tyrosinase, oxidoreductase, unknown function |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 4 |
Total formula weight | 215123.04 |
Authors | Lai, X.,Soler-Lopez, M.,Wichers, H.J.,Dijkstra, B.W. (deposition date: 2016-10-29, release date: 2017-07-12, Last modification date: 2022-12-07) |
Primary citation | Lai, X.,Wichers, H.J.,Soler-Lopez, M.,Dijkstra, B.W. Structure of Human Tyrosinase Related Protein 1 Reveals a Binuclear Zinc Active Site Important for Melanogenesis. Angew. Chem. Int. Ed. Engl., 56:9812-9815, 2017 Cited by PubMed: 28661582DOI: 10.1002/anie.201704616 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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