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5M06

Crystal structure of Mycobacterium tuberculosis PknI kinase domain

Summary for 5M06
Entry DOI10.2210/pdb5m06/pdb
DescriptorSerine/threonine-protein kinase PknI, ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, ... (4 entities in total)
Functional Keywordstuberculosis, kinase, signalling, signaling protein
Biological sourceMycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Cellular locationCytoplasm : P9WI69
Total number of polymer chains2
Total formula weight59808.23
Authors
Wagner, T.,Lisa, M.N.,Alexandre, M.,Barilone, N.,Raynal, B.,Alzari, P.M.,Bellinzoni, M. (deposition date: 2016-10-03, release date: 2017-01-11, Last modification date: 2024-05-01)
Primary citationLisa, M.N.,Wagner, T.,Alexandre, M.,Barilone, N.,Raynal, B.,Alzari, P.M.,Bellinzoni, M.
The crystal structure of PknI from Mycobacterium tuberculosis shows an inactive, pseudokinase-like conformation.
FEBS J., 284:602-614, 2017
Cited by
PubMed: 28054744
DOI: 10.1111/febs.14003
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2 Å)
Structure validation

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