5LYD
Crystal structure of 1 in complex with tafCPB
Summary for 5LYD
Entry DOI | 10.2210/pdb5lyd/pdb |
Descriptor | Carboxypeptidase B, ZINC ION, (2~{S})-6-azanyl-2-(sulfamoylamino)hexanoic acid, ... (4 entities in total) |
Functional Keywords | tafinized carboxypeptidase b, hydrolase |
Biological source | Sus scrofa (Pig) |
Cellular location | Secreted : P09955 |
Total number of polymer chains | 1 |
Total formula weight | 35412.28 |
Authors | Schreuder, H.,Liesum, A.,Loenze, P. (deposition date: 2016-09-27, release date: 2016-10-26, Last modification date: 2016-12-21) |
Primary citation | Halland, N.,Czech, J.,Czechtizky, W.,Evers, A.,Follmann, M.,Kohlmann, M.,Schreuder, H.A.,Kallus, C. Sulfamide as Zinc Binding Motif in Small Molecule Inhibitors of Activated Thrombin Activatable Fibrinolysis Inhibitor (TAFIa). J. Med. Chem., 59:9567-9573, 2016 Cited by PubMed: 27749053DOI: 10.1021/acs.jmedchem.6b01276 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.02 Å) |
Structure validation
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