5LDG
Isopiperitenone reductase from Mentha piperita in complex with Isopiperitenone and NADP
Summary for 5LDG
Entry DOI | 10.2210/pdb5ldg/pdb |
Descriptor | (-)-isopiperitenone reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, (-)-Isopiperitenone, ... (4 entities in total) |
Functional Keywords | short-chain dehydrogenases/reductases (sdr), rossmann fold, isopiperitenone, isopulegone, oxidoreductase |
Biological source | Mentha piperita (Peppermint) |
Cellular location | Cytoplasm : Q6WAU1 |
Total number of polymer chains | 1 |
Total formula weight | 35473.42 |
Authors | Karuppiah, V.,Toogood, H.S.,Leys, D.,Scrutton, N.S. (deposition date: 2016-06-26, release date: 2016-08-31, Last modification date: 2024-01-10) |
Primary citation | Lygidakis, A.,Karuppiah, V.,Hoeven, R.,Ni Cheallaigh, A.,Leys, D.,Gardiner, J.M.,Toogood, H.S.,Scrutton, N.S. Pinpointing a Mechanistic Switch Between Ketoreduction and "Ene" Reduction in Short-Chain Dehydrogenases/Reductases. Angew.Chem.Int.Ed.Engl., 55:9596-9600, 2016 Cited by PubMed: 27411040DOI: 10.1002/anie.201603785 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.3 Å) |
Structure validation
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