5L4M
Crystal Structure of Human Transthyretin in Complex with 3,5,6-Trichloro-2-pyridinyloxyacetic acid (Triclopyr)
Summary for 5L4M
Entry DOI | 10.2210/pdb5l4m/pdb |
Related | 1F41 |
Descriptor | Transthyretin, Triclopyr, SODIUM ION, ... (4 entities in total) |
Functional Keywords | transport protein, thyroxine binding, 3, 5, 6-trichloro-2-pyridinyloxyacetic acid (triclopyr) complex |
Biological source | Homo sapiens (Human) |
Cellular location | Secreted: P02766 |
Total number of polymer chains | 2 |
Total formula weight | 28090.65 |
Authors | Grundstrom, C.,Hall, M.,Zhang, J.,Olofsson, A.,Andersson, P.,Sauer-Eriksson, A.E. (deposition date: 2016-05-25, release date: 2016-10-05, Last modification date: 2024-01-10) |
Primary citation | Zhang, J.,Begum, A.,Brannstrom, K.,Grundstrom, C.,Iakovleva, I.,Olofsson, A.,Sauer-Eriksson, A.E.,Andersson, P.L. Structure-Based Virtual Screening Protocol for in Silico Identification of Potential Thyroid Disrupting Chemicals Targeting Transthyretin. Environ. Sci. Technol., 50:11984-11993, 2016 Cited by PubMed: 27668830DOI: 10.1021/acs.est.6b02771 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.581 Å) |
Structure validation
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