5KVS
Substrate Analog and NADP+ bound structure of Irp3, a Thiazolinyl Imine Reductase from Yersinia enterocolitica
Summary for 5KVS
Entry DOI | 10.2210/pdb5kvs/pdb |
Related | 5KVQ |
Descriptor | Irp3 protein, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, (4~{R})-2-[2-(2-hydroxyphenyl)-1,3-thiazol-4-yl]-4,5-dihydro-1,3-thiazole-4-carboxylic acid, ... (6 entities in total) |
Functional Keywords | imine reductase, oxidoreductase, irp3, siderophore, substrate analog, hptt-cooh, yersiniabactin |
Biological source | Yersinia enterocolitica |
Total number of polymer chains | 2 |
Total formula weight | 88169.42 |
Authors | Meneely, K.M.,Lamb, A.L. (deposition date: 2016-07-15, release date: 2016-09-21, Last modification date: 2023-10-04) |
Primary citation | Meneely, K.M.,Ronnebaum, T.A.,Riley, A.P.,Prisinzano, T.E.,Lamb, A.L. Holo Structure and Steady State Kinetics of the Thiazolinyl Imine Reductases for Siderophore Biosynthesis. Biochemistry, 55:5423-5433, 2016 Cited by PubMed: 27601130DOI: 10.1021/acs.biochem.6b00735 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.28 Å) |
Structure validation
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