5KAS

Murine acid sphingomyelinase-like phosphodiesterase 3b (SMPDL3B) with phosphocholine

Summary for 5KAS

Entry DOI	10.2210/pdb5kas/pdb
Related	5KAR
Descriptor	Acid sphingomyelinase-like phosphodiesterase 3b, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
Functional Keywords	phosphoesterase, extracellular, membrane, phosphocholine, hydrolase
Biological source	Mus musculus (Mouse)
Total number of polymer chains	1
Total formula weight	51193.46
Authors	Gorelik, A.,Illes, K.,Heinz, L.X.,Superti-Furga, G.,Nagar, B. (deposition date: 2016-06-02, release date: 2016-10-05, Last modification date: 2020-07-29)
Primary citation	Gorelik, A.,Heinz, L.X.,Illes, K.,Superti-Furga, G.,Nagar, B. Crystal Structure of the Acid Sphingomyelinase-like Phosphodiesterase SMPDL3B Provides Insights into Determinants of Substrate Specificity. J.Biol.Chem., 291:24054-24064, 2016 Cited by PubMed: 27687724 DOI: 10.1074/jbc.M116.755801 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.619 Å)

Structure validation