5K59
Crystal structure of LukGH from Staphylococcus aureus in complex with a neutralising antibody
Summary for 5K59
Entry DOI | 10.2210/pdb5k59/pdb |
Related | 4TW1 |
Descriptor | Uncharacterized leukocidin-like protein 2, Uncharacterized leukocidin-like protein 1, Fab heavy chain, ... (8 entities in total) |
Functional Keywords | toxin neutralizing monoclonal antibody, conformational epitope, x-ray crystal structure, immune system |
Biological source | Staphylococcus aureus (strain USA300) More |
Total number of polymer chains | 8 |
Total formula weight | 241271.82 |
Authors | Welin, M.,Logan, D.T.,Badarau, A.,Mirkina, I.,Zauner, G.,Dolezilkova, I.,Nagy, E. (deposition date: 2016-05-23, release date: 2016-08-10, Last modification date: 2018-01-17) |
Primary citation | Badarau, A.,Rouha, H.,Malafa, S.,Battles, M.B.,Walker, L.,Nielson, N.,Dolezilkova, I.,Teubenbacher, A.,Banerjee, S.,Maierhofer, B.,Weber, S.,Stulik, L.,Logan, D.T.,Welin, M.,Mirkina, I.,Pleban, C.,Zauner, G.,Gross, K.,Jagerhofer, M.,Magyarics, Z.,Nagy, E. Context matters: The importance of dimerization-induced conformation of the LukGH leukocidin of Staphylococcus aureus for the generation of neutralizing antibodies. Mabs, 8:1347-1360, 2016 Cited by PubMed: 27467113DOI: 10.1080/19420862.2016.1215791 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.84 Å) |
Structure validation
Download full validation report