5JS1

Human Argonaute2 Bound to an siRNA

Summary for 5JS1

• Entry DOI: 10.2210/pdb5js1/pdb
• Related: 5JS2
• Descriptor: Protein argonaute-2, siRNA, PHENOL, ... (5 entities in total)
• Functional Keywords: argonaute, sirna, rnai, nuclease, hydrolase-rna complex, hydrolase/rna
• Biological source: Homo sapiens (Human); More
• Cellular location: Cytoplasm, P-body: Q9UKV8
• Total number of polymer chains: 2
• Total formula weight: 104274.70

Authors

Schirle, N.T.,MacRae, I.J. (deposition date: 2016-05-07, release date: 2016-07-20, Last modification date: 2023-09-27)

• Primary citation: Schirle, N.T.,Kinberger, G.A.,Murray, H.F.,Lima, W.F.,Prakash, T.P.,MacRae, I.J.; Structural Analysis of Human Argonaute-2 Bound to a Modified siRNA Guide.; J.Am.Chem.Soc., 138:8694-8697, 2016; PubMed: 27380263; DOI: 10.1021/jacs.6b04454

Experimental method

X-RAY DIFFRACTION (2.499 Å)