5JCW
Crystal Structure of hGSTP1-1 with Glutathione Adduct of Phenethyl Isothiocyanate
Summary for 5JCW
Entry DOI | 10.2210/pdb5jcw/pdb |
Related | 5JCU |
Descriptor | Glutathione S-transferase P, L-gamma-glutamyl-S-[(2-phenylethyl)carbamothioyl]-L-cysteinylglycine, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (7 entities in total) |
Functional Keywords | gst, peitc, glutathione adduct, transferase |
Biological source | Homo sapiens (Human) |
Cellular location | Cytoplasm : P09211 |
Total number of polymer chains | 2 |
Total formula weight | 48679.05 |
Authors | Kumari, V.,Ji, X. (deposition date: 2016-04-15, release date: 2016-10-12, Last modification date: 2023-09-27) |
Primary citation | Kumari, V.,Dyba, M.A.,Holland, R.J.,Liang, Y.H.,Singh, S.V.,Ji, X. Irreversible Inhibition of Glutathione S-Transferase by Phenethyl Isothiocyanate (PEITC), a Dietary Cancer Chemopreventive Phytochemical. Plos One, 11:e0163821-e0163821, 2016 Cited by PubMed: 27684484DOI: 10.1371/journal.pone.0163821 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.945 Å) |
Structure validation
Download full validation report