5IEW
NMR Structures Show Unwinding of the GCN4p Coiled Coil Superhelix Accompanying Disruption of Ion Pairs at Acidic pH
Summary for 5IEW
Entry DOI | 10.2210/pdb5iew/pdb |
NMR Information | BMRB: 30027 |
Descriptor | General control protein GCN4 (1 entity in total) |
Functional Keywords | supercoil parameters, leucine zipper, salt bridge, closely related nmr structures, conformational transition, electrostatics, knobs-into-holes, canonical alpha helix, transcription |
Biological source | Saccharomyces cerevisiae (Baker's yeast) |
Cellular location | Nucleus: P03069 |
Total number of polymer chains | 2 |
Total formula weight | 7670.81 |
Authors | Brady, M.R.,Kaplan, A.R.,Alexandrescu, A.T. (deposition date: 2016-02-25, release date: 2017-03-15, Last modification date: 2024-05-01) |
Primary citation | Kaplan, A.R.,Brady, M.R.,Maciejewski, M.W.,Kammerer, R.A.,Alexandrescu, A.T. Nuclear Magnetic Resonance Structures of GCN4p Are Largely Conserved When Ion Pairs Are Disrupted at Acidic pH but Show a Relaxation of the Coiled Coil Superhelix. Biochemistry, 56:1604-1619, 2017 Cited by PubMed: 28230348DOI: 10.1021/acs.biochem.6b00634 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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