5I25
human recombinant coagulation FXI in complex with a peptide derived from human high molecular weight kininogen (HKP)
Summary for 5I25
Entry DOI | 10.2210/pdb5i25/pdb |
Related | 5EOD 5EOK |
Descriptor | Coagulation factor XI, ASN-PRO-ILE-SER-ASP-PHE-PRO-ASP, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total) |
Functional Keywords | coagulation fxi, high molecular weight kininogen, hydrolase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 69684.17 |
Authors | Hall, G.A.F.,Wong, S.S.,Emsley, J. (deposition date: 2016-02-08, release date: 2016-04-06, Last modification date: 2020-07-29) |
Primary citation | Wong, S.S.,stergaard, S.,Hall, G.,Li, C.,Williams, P.M.,Stennicke, H.,Emsley, J. A novel DFP tripeptide motif interacts with the coagulation factor XI apple 2 domain. Blood, 127:2915-2923, 2016 Cited by PubMed: 27006387DOI: 10.1182/blood-2015-10-676122 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.85 Å) |
Structure validation
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