5H9S
Crystal Structure of Human Galectin-7 in Complex with TAZTDG
Summary for 5H9S
Entry DOI | 10.2210/pdb5h9s/pdb |
Related | 4XBQ 5H9P 5H9Q 5H9R |
Descriptor | Galectin-7, (2~{S},3~{R},4~{S},5~{R},6~{R})-2-[(2~{S},3~{R},4~{S},5~{R},6~{R})-4-[4-(3-fluorophenyl)-1,2,3-triazol-1-yl]-6-(hydroxymethyl)-3,5-bis(oxidanyl)oxan-2-yl]sulfanyl-6-(hydroxymethyl)oxane-3,4,5-triol (3 entities in total) |
Functional Keywords | galectin, thio-digalactoside (tdg), pi-arginine interaction, fluorine bonding, sugar binding protein |
Biological source | Homo sapiens (Human) |
Cellular location | Cytoplasm : P47929 |
Total number of polymer chains | 2 |
Total formula weight | 34777.94 |
Authors | Hsieh, T.J.,Lin, H.Y.,Lin, C.H. (deposition date: 2015-12-29, release date: 2016-06-29, Last modification date: 2023-11-08) |
Primary citation | Hsieh, T.J.,Lin, H.Y.,Tu, Z.,Lin, T.C.,Wu, S.C.,Tseng, Y.Y.,Liu, F.T.,Danny Hsu, S.T.,Lin, C.H. Dual thio-digalactoside-binding modes of human galectins as the structural basis for the design of potent and selective inhibitors Sci Rep, 6:29457-29457, 2016 Cited by PubMed: 27416897DOI: 10.1038/srep29457 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.821 Å) |
Structure validation
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