5H8M
Crystal structure of Mycobacterium tuberculosis malate synthase C619A, G459A mutant in complex with product malate
Summary for 5H8M
| Entry DOI | 10.2210/pdb5h8m/pdb |
| Related | 5H8P 5H8U |
| Descriptor | Malate synthase G, MAGNESIUM ION, (2S)-2-hydroxybutanedioic acid, ... (4 entities in total) |
| Functional Keywords | transferase-transferase inhibitor complex, transferase/transferase inhibitor |
| Biological source | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) |
| Cellular location | Cytoplasm : P9WK17 |
| Total number of polymer chains | 1 |
| Total formula weight | 80629.15 |
| Authors | Krieger, I.V.,Huang, H.-L.,Sacchettini, J.C. (deposition date: 2015-12-23, release date: 2016-10-26, Last modification date: 2023-09-27) |
| Primary citation | Huang, H.L.,Krieger, I.V.,Parai, M.K.,Gawandi, V.B.,Sacchettini, J.C. Mycobacterium tuberculosis Malate Synthase Structures with Fragments Reveal a Portal for Substrate/Product Exchange. J. Biol. Chem., 291:27421-27432, 2016 Cited by PubMed: 27738104DOI: 10.1074/jbc.M116.750877 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
Download full validation report
