5H02
Crystal structure of Methanohalophilus portucalensis glycine sarcosine N-methyltransferase tetramutant (H21G, E23T, E24N, L28S)
Summary for 5H02
Entry DOI | 10.2210/pdb5h02/pdb |
Descriptor | Glycine sarcosine N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, TRIMETHYL GLYCINE, ... (4 entities in total) |
Functional Keywords | s-adenosylmethionine-dependent methyltransferases, sam, adomet-mtase, class i monomethylation, glycine, sarcosine, rate-limiting enzyme, betaine biosynthesis, betaine-mediated feedback inhibition, transferase |
Biological source | Methanohalophilus portucalensis FDF-1 |
Total number of polymer chains | 1 |
Total formula weight | 33139.61 |
Authors | |
Primary citation | Lee, Y.R.,Lin, T.S.,Lai, S.J.,Liu, M.S.,Lai, M.C.,Chan, N.L. Structural Analysis of Glycine Sarcosine N-methyltransferase from Methanohalophilus portucalensis Reveals Mechanistic Insights into the Regulation of Methyltransferase Activity. Sci Rep, 6:38071-38071, 2016 Cited by PubMed: 27934872DOI: 10.1038/srep38071 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.776 Å) |
Structure validation
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