5GV5
Crystal structure of Candida antarctica Lipase B with active Ser105 modified with a phosphonate inhibitor
Summary for 5GV5
Entry DOI | 10.2210/pdb5gv5/pdb |
Descriptor | Lipase B, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total) |
Functional Keywords | lipase, inhibitor, phosphonate, cal-b, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Pseudozyma antarctica |
Total number of polymer chains | 8 |
Total formula weight | 270940.08 |
Authors | Park, S.Y.,Lee, H. (deposition date: 2016-09-02, release date: 2017-09-13, Last modification date: 2020-07-29) |
Primary citation | Park, K.,Kim, S.,Park, J.,Joe, S.,Min, B.,Oh, J.,Song, J.,Park, S.Y.,Park, S.,Lee, H. Structural and Experimental Evidence for the Enantiomeric Recognition toward a Bulky sec-Alcohol by Candida antarctica Lipase B Acs Catalysis, 6:7458-7465, 2016 Cited by DOI: 10.1021/acscatal.6b02192PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.89 Å) |
Structure validation
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