5GS0
Crystal structure of the complex of TLR3 and bi-specific diabody
Summary for 5GS0
Entry DOI | 10.2210/pdb5gs0/pdb |
Related | 5GRU 5GRV 5GRW 5GRX 5GRY 5GRZ 5GS1 5GS2 5GS3 |
Descriptor | Toll-like receptor 3, light chain (anti-TLR3), heavy chain (anti-TLR3), ... (8 entities in total) |
Functional Keywords | diabody, antibody fragment, complex, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 10 |
Total formula weight | 262271.39 |
Authors | Kim, J.H.,Song, D.H.,Youn, S.J.,Kim, J.W.,Cho, G.,Lee, H.,Lee, J.O. (deposition date: 2016-08-13, release date: 2016-10-12, Last modification date: 2024-03-20) |
Primary citation | Kim, J.H.,Song, D.H.,Youn, S.J.,Kim, J.W.,Cho, G.,Kim, S.C.,Lee, H.,Jin, M.S.,Lee, J.O. Crystal structure of mono- and bi-specific diabodies and reduction of their structural flexibility by introduction of disulfide bridges at the Fv interface. Sci Rep, 6:34515-34515, 2016 Cited by PubMed: 27682821DOI: 10.1038/srep34515 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.275 Å) |
Structure validation
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