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5GRE

Crystal structure of the alpha gamma heterodimer of human IDH3 in complex with Mg(2+), citrate and ADP

Summary for 5GRE
Entry DOI10.2210/pdb5gre/pdb
Related5GRF 5GRH 5GRI 5GRL
DescriptorIsocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial, MAGNESIUM ION, ... (6 entities in total)
Functional Keywordscit, adp, allosteric regulation, oxidoreductase
Biological sourceHomo sapiens (Human)
More
Cellular locationMitochondrion: P50213 P51553
Total number of polymer chains2
Total formula weight76217.63
Authors
Ma, T.,Peng, Y.,Ding, J. (deposition date: 2016-08-11, release date: 2017-02-15, Last modification date: 2023-11-08)
Primary citationMa, T.,Peng, Y.,Huang, W.,Ding, J.
Molecular mechanism of the allosteric regulation of the alpha gamma heterodimer of human NAD-dependent isocitrate dehydrogenase.
Sci Rep, 7:40921-40921, 2017
Cited by
PubMed: 28098230
DOI: 10.1038/srep40921
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.65 Å)
Structure validation

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