5FIT
FHIT-SUBSTRATE ANALOG
Summary for 5FIT
Entry DOI | 10.2210/pdb5fit/pdb |
Descriptor | FRAGILE HISTIDINE TRIAD PROTEIN, PHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER (3 entities in total) |
Functional Keywords | hydrolase, fragile histidine triad protein, fhit, putative tumor suppressor, hit protein family, histidine triad protein family, nucleotidyl hydrolase, nucleotidyl transferase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P49789 |
Total number of polymer chains | 1 |
Total formula weight | 17405.22 |
Authors | Lima, C.D.,Klein, M.G.,Hendrickson, W.A. (deposition date: 1997-09-25, release date: 1998-03-25, Last modification date: 2024-06-05) |
Primary citation | Lima, C.D.,Klein, M.G.,Hendrickson, W.A. Structure-based analysis of catalysis and substrate definition in the HIT protein family. Science, 278:286-290, 1997 Cited by PubMed: 9323207DOI: 10.1126/science.278.5336.286 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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