5F3Z
Dengue serotype 3 RNA-dependent RNA polymerase bound to PC-79-SH52
Summary for 5F3Z
Entry DOI | 10.2210/pdb5f3z/pdb |
Related | 5F3T 5F41 |
Descriptor | Genome polyprotein, ZINC ION, 2-(4-methoxy-3-thiophen-2-yl-phenyl)ethanoic acid, ... (4 entities in total) |
Functional Keywords | rdrp inhibitor, dengue, transferase |
Biological source | Dengue virus 3 |
Cellular location | Virion membrane ; Multi-pass membrane protein : Q6DLV0 |
Total number of polymer chains | 1 |
Total formula weight | 74003.98 |
Authors | Noble, C.G. (deposition date: 2015-12-03, release date: 2016-02-24, Last modification date: 2023-11-08) |
Primary citation | Noble, C.G.,Lim, S.P.,Arora, R.,Yokokawa, F.,Nilar, S.,Seh, C.C.,Wright, S.K.,Benson, T.E.,Smith, P.W.,Shi, P.Y. A Conserved Pocket in the Dengue Virus Polymerase Identified through Fragment-based Screening J.Biol.Chem., 291:8541-8548, 2016 Cited by PubMed: 26872970DOI: 10.1074/jbc.M115.710731 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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