5E13
Crystal structure of Eosinophil-derived neurotoxin in complex with the triazole double-headed ribonucleoside 11c
Summary for 5E13
Entry DOI | 10.2210/pdb5e13/pdb |
Descriptor | Non-secretory ribonuclease, 3'-{4-[(4-amino-2-oxopyrimidin-1(2H)-yl)methyl]-1H-1,2,3-triazol-1-yl}-3'-deoxyadenosine (3 entities in total) |
Functional Keywords | hydrolase, nuclease |
Biological source | Homo sapiens (Human) |
Cellular location | Lysosome : P10153 |
Total number of polymer chains | 1 |
Total formula weight | 18846.64 |
Authors | Chatzileontiadou, D.S.M.,Stravodimos, G.A.,Kantsadi, A.L.,Leonidas, D.D. (deposition date: 2015-09-29, release date: 2015-11-18, Last modification date: 2024-01-10) |
Primary citation | Chatzileontiadou, D.S.,Parmenopoulou, V.,Manta, S.,Kantsadi, A.L.,Kylindri, P.,Griniezaki, M.,Kontopoulou, F.,Telopoulou, A.,Prokova, H.,Panagopoulos, D.,Boix, E.,Balatsos, N.A.,Komiotis, D.,Leonidas, D.D. Triazole double-headed ribonucleosides as inhibitors of eosinophil derived neurotoxin. Bioorg.Chem., 63:152-165, 2015 Cited by PubMed: 26551065DOI: 10.1016/j.bioorg.2015.10.007 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.34 Å) |
Structure validation
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