5DX7
Crystal structure of Mycobacterium tuberculosis malate synthase in complex with 5-(5-chlorothiophen-2-yl)isoxazole-3-carboxylic acid
Summary for 5DX7
Entry DOI | 10.2210/pdb5dx7/pdb |
Related | 5DRC 5DRI |
Descriptor | Malate synthase G, MAGNESIUM ION, 5-(5-chlorothiophen-2-yl)-1,2-oxazole-3-carboxylic acid, ... (4 entities in total) |
Functional Keywords | acetyltransferase, transferase |
Biological source | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) |
Cellular location | Cytoplasm : P9WK17 |
Total number of polymer chains | 1 |
Total formula weight | 80710.68 |
Authors | Huang, H.-L.,Sacchettini, J.C. (deposition date: 2015-09-23, release date: 2016-10-05, Last modification date: 2023-09-27) |
Primary citation | Huang, H.L.,Krieger, I.V.,Parai, M.K.,Gawandi, V.B.,Sacchettini, J.C. Mycobacterium tuberculosis Malate Synthase Structures with Fragments Reveal a Portal for Substrate/Product Exchange. J. Biol. Chem., 291:27421-27432, 2016 Cited by PubMed: 27738104DOI: 10.1074/jbc.M116.750877 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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