5D94

Crystal structure of LC3-LIR peptide complex

Summary for 5D94

Entry DOI	10.2210/pdb5d94/pdb
Descriptor	Microtubule-associated proteins 1A/1B light chain 3B, Peptide from FYVE and coiled-coil domain-containing protein 1 (3 entities in total)
Functional Keywords	fyco1, autophagy, lc3, lir, protein binding-peptide complex, protein binding/peptide
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	16616.04
Authors	Takagi, K.,Mizushima, T.,Johansen, T. (deposition date: 2015-08-18, release date: 2015-10-21, Last modification date: 2024-03-20)
Primary citation	Olsvik, H.L.,Lamark, T.,Takagi, K.,Larsen, K.B.,Evjen, G.,vervatn, A.,Mizushima, T.,Johansen, T. FYCO1 Contains a C-terminally Extended, LC3A/B-preferring LC3-interacting Region (LIR) Motif Required for Efficient Maturation of Autophagosomes during Basal Autophagy J.Biol.Chem., 290:29361-29374, 2015 Cited by PubMed: 26468287 DOI: 10.1074/jbc.M115.686915 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.53 Å)

Structure validation