5CSN

S100B-RSK1 crystal structure C

Summary for 5CSN

• Entry DOI: 10.2210/pdb5csn/pdb
• Descriptor: Protein S100-B, Ribosomal protein S6 kinase alpha-1, CALCIUM ION (3 entities in total)
• Functional Keywords: s100, kinase, signaling, inhibitor, transferase
• Biological source: Homo sapiens (Human); More
• Cellular location: Cytoplasm : P04271; Nucleus: Q15418
• Total number of polymer chains: 3
• Total formula weight: 26382.62

Authors

Gogl, G.,Nyitray, L. (deposition date: 2015-07-23, release date: 2015-11-11, Last modification date: 2024-01-10)

• Primary citation: Gogl, G.,Alexa, A.,Kiss, B.,Katona, G.,Kovacs, M.,Bodor, A.,Remenyi, A.,Nyitray, L.; Structural Basis of Ribosomal S6 Kinase 1 (RSK1) Inhibition by S100B Protein: MODULATION OF THE EXTRACELLULAR SIGNAL-REGULATED KINASE (ERK) SIGNALING CASCADE IN A CALCIUM-DEPENDENT WAY.; J.Biol.Chem., 291:11-27, 2016; PubMed: 26527685; DOI: 10.1074/jbc.M115.684928

Experimental method

X-RAY DIFFRACTION (2.95 Å)