5CJX
Crystal structure of 8ANC195 Fab in complex with BG505 SOSIP.664 HIV-1 Env trimer
Summary for 5CJX
Entry DOI | 10.2210/pdb5cjx/pdb |
Descriptor | 8ANC195 G52K5 heavy chain, IG gamma-1 chain, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (11 entities in total) |
Functional Keywords | hiv-1 env trimer, ig fold, antibody, viral protein-immune system complex, viral protein/immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 12 |
Total formula weight | 377123.55 |
Authors | Scharf, L.,Bjorkman, P.J. (deposition date: 2015-07-15, release date: 2015-09-23, Last modification date: 2023-09-27) |
Primary citation | Scharf, L.,Wang, H.,Gao, H.,Chen, S.,McDowall, A.W.,Bjorkman, P.J. Broadly Neutralizing Antibody 8ANC195 Recognizes Closed and Open States of HIV-1 Env. Cell, 162:1379-1390, 2015 Cited by PubMed: 26359989DOI: 10.1016/j.cell.2015.08.035 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.584 Å) |
Structure validation
Download full validation report