5AMA
Crystal structure of the Angiotensin-1 converting enzyme N-domain in complex with amyloid-beta 1-16
Summary for 5AMA
Entry DOI | 10.2210/pdb5ama/pdb |
Related | 5AM8 5AM9 5AMB 5AMC |
Descriptor | ANGIOTENSIN-CONVERTING ENZYME, CHLORIDE ION, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (14 entities in total) |
Functional Keywords | metalloprotease, amyloid- beta, hydrolase |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 4 |
Total formula weight | 299937.54 |
Authors | Masuyer, G.,Larmuth, K.M.,Douglas, R.G.,Sturrock, E.D.,Acharya, K.R. (deposition date: 2015-03-10, release date: 2016-01-13, Last modification date: 2024-01-10) |
Primary citation | Larmuth, K.M.,Masuyer, G.,Douglas, R.G.,Sturrock, E.D.,Acharya, K.R. The Kinetic and Structural Characterisation of Amyloid-Beta Metabolism by Human Angiotensin-1- Converting Enzyme (Ace) FEBS J., 283:1060-, 2016 Cited by PubMed: 26748546DOI: 10.1111/FEBS.13647 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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