5AGX
Bcl-2 alpha beta-1 LINEAR complex
Summary for 5AGX
Entry DOI | 10.2210/pdb5agx/pdb |
Related | 5AGW |
Descriptor | APOPTOSIS REGULATOR BCL-2, BCL-2-LIKE PROTEIN 1, APOPTOSIS REGULATOR BCL-2, BCL-2-LIKE PROTEIN 11, ... (4 entities in total) |
Functional Keywords | foldamer, bim, apoptosis |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Mitochondrion outer membrane ; Single-pass membrane protein : P10415 Q07817 Endomembrane system ; Peripheral membrane protein . Isoform BimEL: Mitochondrion. Isoform BimL: Mitochondrion. Isoform BimS: Mitochondrion. Isoform Bim-alpha1: Mitochondrion: P10415 |
Total number of polymer chains | 4 |
Total formula weight | 44137.49 |
Authors | Smith, B.J.,F Lee, E.,Checco, J.W.,Gellman, S.H.,Fairlie, W.D. (deposition date: 2015-02-04, release date: 2015-09-09, Last modification date: 2024-05-01) |
Primary citation | Checco, J.W.,Lee, E.F.,Evangelista, M.,Sleebs, N.,Rodgers, K.,Pettikiriarachchi, A.,Kershaw, N.,Eddinger, G.A.,Belair, D.G.,Wilson, J.L.,Eller, C.H.,Raines, R.T.,Murphy, W.L.,Smith, B.J.,Gellman, S.H.,Fairlie, W.D. Alpha Beta Peptide Foldamers Targeting Intracellular Protein-Protein Interactions with Activity on Living Cells J.Am.Chem.Soc., 137:11365-, 2015 Cited by PubMed: 26317395DOI: 10.1021/JACS.5B05896 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.24 Å) |
Structure validation
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