5A0E
Crystal structure of cyclophilin D in complex with CsA analogue, JW47.
Summary for 5A0E
Entry DOI | 10.2210/pdb5a0e/pdb |
Descriptor | PEPTIDYL-PROLYL CIS-TRANS ISOMERASE F, MITOCHONDRIAL, JW47 (3 entities in total) |
Functional Keywords | isomerase, cyclophilin d, cyp d, ppif, cyclosporin a, csa, jw47, mitochondrial permeability transition pore, ptp, peptidylprolyl cis-trans isomerase, cyclophilin |
Biological source | HOMO SAPIENS (HUMAN) More |
Total number of polymer chains | 4 |
Total formula weight | 38232.07 |
Authors | Warne, J.,Pryce, G.,Hill, J.,Shi, X.,Lenneras, F.,Puentes, F.,Kip, M.,Hilditch, L.,Walker, P.,Simone, M.,Chan, A.W.E.,Towers, G.,Coker, A.R.,Duchen, M.,Szabadkai, G.,Baker, D.,Selwood, D.L. (deposition date: 2015-04-19, release date: 2015-12-30, Last modification date: 2024-01-10) |
Primary citation | Warne, J.,Pryce, G.,Hill, J.,Shi, X.,Lenneras, F.,Puentes, F.,Kip, M.,Hilditch, L.,Walker, P.,Simone, M.I.,Chan, A.W.E.,Towers, G.J.,Coker, A.R.,Duchen, M.R.,Szabadkai, G.,Baker, D.,Selwood, D.L. Selective Inhibition of the Mitochondrial Permeability Transition Pore Protects Against Neuro-Degeneration in Experimental Multiple Sclerosis. J.Biol.Chem., 291:4356-, 2016 Cited by PubMed: 26679998DOI: 10.1074/JBC.M115.700385 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.25 Å) |
Structure validation
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