521P
THREE-DIMENSIONAL STRUCTURES OF H-RAS P21 MUTANTS: MOLECULAR BASIS FOR THEIR INABILITY TO FUNCTION AS SIGNAL SWITCH MOLECULES
Summary for 521P
Entry DOI | 10.2210/pdb521p/pdb |
Descriptor | H-RAS P21 PROTEIN, MAGNESIUM ION, GUANOSINE-5'-TRIPHOSPHATE (3 entities in total) |
Functional Keywords | oncogene protein |
Biological source | Homo sapiens (human) |
Cellular location | Cell membrane. Isoform 2: Nucleus: P01112 |
Total number of polymer chains | 1 |
Total formula weight | 19494.78 |
Authors | Schlichting, I.,Krengel, U.,Kabsch, W.,Wittinghofer, A.,Pai, E.F. (deposition date: 1991-06-06, release date: 1994-01-31, Last modification date: 2024-03-06) |
Primary citation | Krengel, U.,Schlichting, I.,Scherer, A.,Schumann, R.,Frech, M.,John, J.,Kabsch, W.,Pai, E.F.,Wittinghofer, A. Three-dimensional structures of H-ras p21 mutants: molecular basis for their inability to function as signal switch molecules. Cell(Cambridge,Mass.), 62:539-548, 1990 Cited by PubMed: 2199064DOI: 10.1016/0092-8674(90)90018-A PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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