521P

THREE-DIMENSIONAL STRUCTURES OF H-RAS P21 MUTANTS: MOLECULAR BASIS FOR THEIR INABILITY TO FUNCTION AS SIGNAL SWITCH MOLECULES

521P の概要

• エントリーDOI: 10.2210/pdb521p/pdb
• 分子名称: H-RAS P21 PROTEIN, MAGNESIUM ION, GUANOSINE-5'-TRIPHOSPHATE (3 entities in total)
• 機能のキーワード: oncogene protein
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cell membrane. Isoform 2: Nucleus: P01112
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 19494.78

構造登録者

Schlichting, I.,Krengel, U.,Kabsch, W.,Wittinghofer, A.,Pai, E.F. (登録日: 1991-06-06, 公開日: 1994-01-31, 最終更新日: 2024-03-06)

• 主引用文献: Krengel, U.,Schlichting, I.,Scherer, A.,Schumann, R.,Frech, M.,John, J.,Kabsch, W.,Pai, E.F.,Wittinghofer, A.; Three-dimensional structures of H-ras p21 mutants: molecular basis for their inability to function as signal switch molecules.; Cell(Cambridge,Mass.), 62:539-548, 1990; PubMed: 2199064; DOI: 10.1016/0092-8674(90)90018-A

実験手法

X-RAY DIFFRACTION (2.6 Å)