4ZYR

Crystal structure of E. coli Lactose permease G46W/G262W bound to p-nitrophenyl alpha-D-galactopyranoside (alpha-NPG)

4ZYR の概要

• エントリーDOI: 10.2210/pdb4zyr/pdb
• 関連するPDBエントリー: 1PV7 2V8N 2Y5Y 4OAA
• 分子名称: Lactose permease, 4-nitrophenyl alpha-D-galactopyranoside, nonyl beta-D-glucopyranoside (3 entities in total)
• 機能のキーワード: membrane protein, transporter, alpha-helical, major facilitator superfamily (mfs), transport protein
• 由来する生物種: Escherichia coli (strain K12)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 94793.70

構造登録者

Kumar, H.,Finer-Moore, J.S.,Kaback, H.R.,Stroud, R.M. (登録日: 2015-05-22, 公開日: 2015-07-29, 最終更新日: 2023-09-27)

• 主引用文献: Kumar, H.,Finer-Moore, J.S.,Kaback, H.R.,Stroud, R.M.; Structure of LacY with an alpha-substituted galactoside: Connecting the binding site to the protonation site.; Proc.Natl.Acad.Sci.USA, 112:9004-9009, 2015; PubMed: 26157133; DOI: 10.1073/pnas.1509854112

実験手法

X-RAY DIFFRACTION (3.312 Å)