4ZUP

Crystal structure of acetylpolyamine amidohydrolase from Mycoplana ramosa in complex with a hydroxamate inhibitor

4ZUP の概要

• エントリーDOI: 10.2210/pdb4zup/pdb
• 関連するPDBエントリー: 4ZUM 4ZUN 4ZUO 4ZUQ 4ZUR
• 分子名称: Acetylpolyamine aminohydrolase, ZINC ION, POTASSIUM ION, ... (7 entities in total)
• 機能のキーワード: acetylpolyamine amidohydrolase, arginase fold, enzyme-inhibitor complex, polyamine, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Mycoplana ramosa
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 74038.73

構造登録者

Decroos, C.,Christianson, D.W. (登録日: 2015-05-17, 公開日: 2015-07-29, 最終更新日: 2023-09-27)

• 主引用文献: Decroos, C.,Christianson, D.W.; Design, Synthesis, and Evaluation of Polyamine Deacetylase Inhibitors, and High-Resolution Crystal Structures of Their Complexes with Acetylpolyamine Amidohydrolase.; Biochemistry, 54:4692-4703, 2015; PubMed: 26200446; DOI: 10.1021/acs.biochem.5b00536

実験手法

X-RAY DIFFRACTION (1.421 Å)