4ZP3

AKAP18:PKA-RIIalpha structure reveals crucial anchor points for recognition of regulatory subunits of PKA

Summary for 4ZP3

Entry DOI	10.2210/pdb4zp3/pdb
Descriptor	cAMP-dependent protein kinase type II-alpha regulatory subunit, A-kinase anchor protein 7 isoforms alpha and beta, CADMIUM ION, ... (4 entities in total)
Functional Keywords	anchor points, amphiphathic helix, akap, dd-domain, signaling protein
Biological source	Homo sapiens (Human) More
Cellular location	Cytoplasm : P13861 Isoform Alpha: Lateral cell membrane; Lipid- anchor. Isoform Beta: Apical cell membrane; Lipid- anchor: O43687
Total number of polymer chains	18
Total formula weight	87385.71
Authors	Goetz, F.,Roske, Y.,Faelber, K.,Zuehlke, K.,Autenrieth, K.,Kreuchwig, A.,Krause, G.,Herberg, F.W.,Daumke, O.,Heinemann, U.,Klussmann, E. (deposition date: 2015-05-07, release date: 2016-05-04, Last modification date: 2016-07-06)
Primary citation	Gotz, F.,Roske, Y.,Schulz, M.S.,Autenrieth, K.,Bertinetti, D.,Faelber, K.,Zuhlke, K.,Kreuchwig, A.,Kennedy, E.J.,Krause, G.,Daumke, O.,Herberg, F.W.,Heinemann, U.,Klussmann, E. AKAP18:PKA-RII alpha structure reveals crucial anchor points for recognition of regulatory subunits of PKA. Biochem.J., 473:1881-1894, 2016 Cited by PubMed: 27102985 DOI: 10.1042/BCJ20160242 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.63 Å)

Structure validation