4ZNX

Crystal structure of the Fyn-SH3 domain in complex with the high affinity peptide APP12

Summary for 4ZNX

Entry DOI	10.2210/pdb4znx/pdb
Related	3UA6 3UA7 4EIK
Descriptor	Tyrosine-protein kinase Fyn, APP12 (3 entities in total)
Functional Keywords	beta shandwich, signaling protein
Biological source	Homo sapiens (Human) More
Cellular location	Cytoplasm: P06241
Total number of polymer chains	8
Total formula weight	32039.45
Authors	Camara-Artigas, A. (deposition date: 2015-05-05, release date: 2016-06-29, Last modification date: 2024-01-10)
Primary citation	Camara-Artigas, A.,Ortiz-Salmeron, E.,Andujar-Sanchez, M.,Bacarizo, J.,Martin-Garcia, J.M. The role of water molecules in the binding of class I and II peptides to the SH3 domain of the Fyn tyrosine kinase. Acta Crystallogr.,Sect.F, 72:707-712, 2016 Cited by PubMed: 27599862 DOI: 10.1107/S2053230X16012310 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation