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4ZNE

IgG1 Fc-FcgammaRI ecd complex

Summary for 4ZNE
Entry DOI10.2210/pdb4zne/pdb
DescriptorHigh affinity immunoglobulin gamma Fc receptor I, Ig gamma-1 chain C region, alpha-D-mannopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
Functional Keywordsantibody, constant region, receptor, high affinity, immune system
Biological sourceHomo sapiens (Human)
More
Cellular locationCell membrane ; Single-pass type I membrane protein : P12314
Secreted: P01857
Total number of polymer chains3
Total formula weight86124.51
Authors
Oganesyan, V.Y.,Dall'Acqua, W.F. (deposition date: 2015-05-04, release date: 2015-11-11, Last modification date: 2020-07-29)
Primary citationOganesyan, V.,Mazor, Y.,Yang, C.,Cook, K.E.,Woods, R.M.,Ferguson, A.,Bowen, M.A.,Martin, T.,Zhu, J.,Wu, H.,Dall'Acqua, W.F.
Structural insights into the interaction of human IgG1 with Fc gamma RI: no direct role of glycans in binding.
Acta Crystallogr.,Sect.D, 71:2354-2361, 2015
Cited by
PubMed: 26527150
DOI: 10.1107/S1399004715018015
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.42 Å)
Structure validation

217705

數據於2024-03-27公開中

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