4ZNE
IgG1 Fc-FcgammaRI ecd complex
Summary for 4ZNE
Entry DOI | 10.2210/pdb4zne/pdb |
Descriptor | High affinity immunoglobulin gamma Fc receptor I, Ig gamma-1 chain C region, alpha-D-mannopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total) |
Functional Keywords | antibody, constant region, receptor, high affinity, immune system |
Biological source | Homo sapiens (Human) More |
Cellular location | Cell membrane ; Single-pass type I membrane protein : P12314 Secreted: P01857 |
Total number of polymer chains | 3 |
Total formula weight | 86124.51 |
Authors | Oganesyan, V.Y.,Dall'Acqua, W.F. (deposition date: 2015-05-04, release date: 2015-11-11, Last modification date: 2020-07-29) |
Primary citation | Oganesyan, V.,Mazor, Y.,Yang, C.,Cook, K.E.,Woods, R.M.,Ferguson, A.,Bowen, M.A.,Martin, T.,Zhu, J.,Wu, H.,Dall'Acqua, W.F. Structural insights into the interaction of human IgG1 with Fc gamma RI: no direct role of glycans in binding. Acta Crystallogr.,Sect.D, 71:2354-2361, 2015 Cited by PubMed: 26527150DOI: 10.1107/S1399004715018015 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.42 Å) |
Structure validation
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