4ZK6

Crystallographic Capture of Quinolinate Synthase (NadA) from Pyrococcus horikoshii in its Substrates and Product-Bound States

Summary for 4ZK6

Entry DOI	10.2210/pdb4zk6/pdb
Related	4ZKZ 5FEV 5FFK
Descriptor	Quinolinate synthase A, IRON/SULFUR CLUSTER, QUINOLINIC ACID, ... (7 entities in total)
Functional Keywords	quinolicnic acid, biosynthesis of nicotinamide adenine dinucleotide., transferase
Biological source	Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Total number of polymer chains	2
Total formula weight	69698.53
Authors	Esakova, O.A.,Grove, T.L.,Saunders, A.H.,Yennawar, N.H.,Booker, S.J. (deposition date: 2015-04-29, release date: 2016-06-29, Last modification date: 2023-09-27)
Primary citation	Esakova, O.A.,Silakov, A.,Grove, T.L.,Saunders, A.H.,McLaughlin, M.I.,Yennawar, N.H.,Booker, S.J. Structure of Quinolinate Synthase from Pyrococcus horikoshii in the Presence of Its Product, Quinolinic Acid. J.Am.Chem.Soc., 138:7224-7227, 2016 Cited by PubMed: 27224840 DOI: 10.1021/jacs.6b02708 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.895 Å)

Structure validation