4ZK6

Crystallographic Capture of Quinolinate Synthase (NadA) from Pyrococcus horikoshii in its Substrates and Product-Bound States

4ZK6 の概要

• エントリーDOI: 10.2210/pdb4zk6/pdb
• 関連するPDBエントリー: 4ZKZ 5FEV 5FFK
• 分子名称: Quinolinate synthase A, IRON/SULFUR CLUSTER, QUINOLINIC ACID, ... (7 entities in total)
• 機能のキーワード: quinolicnic acid, biosynthesis of nicotinamide adenine dinucleotide., transferase
• 由来する生物種: Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 69698.53

構造登録者

Esakova, O.A.,Grove, T.L.,Saunders, A.H.,Yennawar, N.H.,Booker, S.J. (登録日: 2015-04-29, 公開日: 2016-06-29, 最終更新日: 2023-09-27)

• 主引用文献: Esakova, O.A.,Silakov, A.,Grove, T.L.,Saunders, A.H.,McLaughlin, M.I.,Yennawar, N.H.,Booker, S.J.; Structure of Quinolinate Synthase from Pyrococcus horikoshii in the Presence of Its Product, Quinolinic Acid.; J.Am.Chem.Soc., 138:7224-7227, 2016; PubMed: 27224840; DOI: 10.1021/jacs.6b02708

実験手法

X-RAY DIFFRACTION (1.895 Å)