4ZFO

J22.9-xi: chimeric mouse/human antibody against human BCMA (CD269)

4ZFO の概要

• エントリーDOI: 10.2210/pdb4zfo/pdb
• 分子名称: Tumor necrosis factor receptor superfamily member 17, J22.9-xi Fab, Light Chain, J22.9-xi Fab, Heavy Chain, ... (7 entities in total)
• 機能のキーワード: antibody fab-ligand complex anti-bcma anti-tumor, immune system
• 由来する生物種: Homo sapiens (Human); 詳細
• 細胞内の位置: Cell membrane; Single-pass type III membrane protein: Q02223
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 106712.63

構造登録者

Marino, S.F.,Daumke, O.,Olal, D. (登録日: 2015-04-21, 公開日: 2015-05-20, 最終更新日: 2024-01-10)

• 主引用文献: Oden, F.,Marino, S.F.,Brand, J.,Scheu, S.,Kriegel, C.,Olal, D.,Takvorian, A.,Westermann, J.,Yilmaz, B.,Hinz, M.,Daumke, O.,Hopken, U.E.,Muller, G.,Lipp, M.; Potent anti-tumor response by targeting B cell maturation antigen (BCMA) in a mouse model of multiple myeloma.; Mol Oncol, 9:1348-1358, 2015; PubMed: 25953704; DOI: 10.1016/j.molonc.2015.03.010

実験手法

X-RAY DIFFRACTION (1.895 Å)