4ZEG
Crystal structure of TTK kinase domain in complex with a pyrazolopyrimidine inhibitor
Summary for 4ZEG
Entry DOI | 10.2210/pdb4zeg/pdb |
Descriptor | Dual specificity protein kinase TTK, GLYCEROL, DI(HYDROXYETHYL)ETHER, ... (6 entities in total) |
Functional Keywords | kinase, ttk, inhibitor, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 33542.53 |
Authors | Qiu, W.,Plotnikova, O.,Feher, M.,Awrey, D.E.,Battaile, K.,Chirgadze, N.Y. (deposition date: 2015-04-20, release date: 2016-04-27, Last modification date: 2024-03-06) |
Primary citation | Qiu, W.,Plotnikova, O.,Feher, M.,Awrey, D.E.,Battaile, K.,Chirgadze, N.Y. Crystal structure of TTK kinase domain in complex with a pyrazolopyrimidine inhibitor. To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.33 Å) |
Structure validation
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