4ZEE

X-ray structure of the bis-platinum lysozyme adduct formed in the reaction between the protein and the two drugs Cisplatin and Oxaliplatin (preparation 2)

4ZEE の概要

• エントリーDOI: 10.2210/pdb4zee/pdb
• 分子名称: Lysozyme C, NITRATE ION, 1,2-ETHANEDIOL, ... (6 entities in total)
• 機能のキーワード: ciapltin, oxaliplatin, platin based drugs, cancer, hydrolase
• 由来する生物種: Gallus gallus (Chicken)
• 細胞内の位置: Secreted: P00698
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 15622.65

構造登録者

Merlino, A. (登録日: 2015-04-20, 公開日: 2015-05-27, 最終更新日: 2024-01-10)

• 主引用文献: Marasco, D.,Messori, L.,Marzo, T.,Merlino, A.; Oxaliplatin vs. cisplatin: competition experiments on their binding to lysozyme.; Dalton Trans, 44:10392-10398, 2015; PubMed: 25974859; DOI: 10.1039/c5dt01279a

実験手法

X-RAY DIFFRACTION (1.95 Å)