4ZCQ

Crystal structure of the C-terminal catalytic domain of Plasmodium falciparum CTP:phosphocholine cytidylyltransferase in complex with choline

Summary for 4ZCQ

Entry DOI	10.2210/pdb4zcq/pdb
Related	4ZCP
Descriptor	Cholinephosphate cytidylyltransferase, CHOLINE ION (3 entities in total)
Functional Keywords	enzyme, malaria, cytidylyltransferase, phosphatidylcholine, transferase
Biological source	Plasmodium falciparum
Total number of polymer chains	1
Total formula weight	20914.29
Authors	Guca, E.,Hoh, F.,Guichou, J.-F.,Cerdan, R. (deposition date: 2015-04-16, release date: 2016-09-14, Last modification date: 2024-01-10)
Primary citation	Guca, E.,Nagy, G.N.,Hajdu, F.,Marton, L.,Izrael, R.,Hoh, F.,Yang, Y.,Vial, H.,Vertessy, B.G.,Guichou, J.F.,Cerdan, R. Structural determinants of the catalytic mechanism of Plasmodium CCT, a key enzyme of malaria lipid biosynthesis. Sci Rep, 8:11215-11215, 2018 Cited by PubMed: 30046154 DOI: 10.1038/s41598-018-29500-9 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.92 Å)

Structure validation