4ZC6

Crystal Structure of human GGT1 in complex with Serine Borate

4ZC6 の概要

• エントリーDOI: 10.2210/pdb4zc6/pdb
• 分子名称: Gamma-glutamyltranspeptidase 1 heavy chain, Gamma-glutamyltranspeptidase 1 light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• 機能のキーワード: ntn-hydrolase family, glycoprotein, n- glycosylation, cell surface, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 60135.16

構造登録者

Terzyan, S.,Hanigan, M. (登録日: 2015-04-15, 公開日: 2015-06-03, 最終更新日: 2023-09-27)

• 主引用文献: Terzyan, S.S.,Burgett, A.W.,Heroux, A.,Smith, C.A.,Mooers, B.H.,Hanigan, M.H.; Human gamma-Glutamyl Transpeptidase 1: STRUCTURES OF THE FREE ENZYME, INHIBITOR-BOUND TETRAHEDRAL TRANSITION STATES, AND GLUTAMATE-BOUND ENZYME REVEAL NOVEL MOVEMENT WITHIN THE ACTIVE SITE DURING CATALYSIS.; J.Biol.Chem., 290:17576-17586, 2015; PubMed: 26013825; DOI: 10.1074/jbc.M115.659680

実験手法