4ZAH

Crystal structure of sugar aminotransferase WecE with External Aldimine VII from Escherichia coli K-12

「4WFP」から置き換えられました

4ZAH の概要

• エントリーDOI: 10.2210/pdb4zah/pdb
• 関連するPDBエントリー: 4PIW
• 分子名称: dTDP-4-amino-4,6-dideoxygalactose transaminase, [[(2R,3S,5R)-5-[5-methyl-2,4-bis(oxidanylidene)pyrimidin-1-yl]-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2R,3R,4S,5R,6R)-6-methyl-5-[(E)-[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylideneamino]-3,4-bis(oxidanyl)oxan-2-yl] hydrogen phosphate (3 entities in total)
• 機能のキーワード: sugar aminotransferase, structural genomics, psi-biology, protein structure initiative, enzyme discovery for natural product biosynthesis, natpro, transferase
• 由来する生物種: Escherichia coli (strain K12)
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 359149.90

構造登録者

Wang, F.,Singh, S.,Cao, H.,Xu, W.,Miller, M.D.,Thorson, J.S.,Phillips Jr., G.N.,Enzyme Discovery for Natural Product Biosynthesis (NatPro) (登録日: 2015-04-13, 公開日: 2015-04-29, 最終更新日: 2023-09-27)

• 主引用文献: Wang, F.,Singh, S.,Xu, W.,Helmich, K.E.,Miller, M.D.,Cao, H.,Bingman, C.A.,Thorson, J.S.,Phillips, G.N.; Structural Basis for the Stereochemical Control of Amine Installation in Nucleotide Sugar Aminotransferases.; Acs Chem.Biol., 10:2048-2056, 2015; PubMed: 26023720; DOI: 10.1021/acschembio.5b00244

実験手法

X-RAY DIFFRACTION (2.24 Å)