Summary for 4Z9L
Entry DOI | 10.2210/pdb4z9l/pdb |
Related | 1PMQ |
Descriptor | Mitogen-activated protein kinase 10, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, CYCLOHEXYL-{4-[5-(3,4-DICHLOROPHENYL)-2-PIPERIDIN-4-YL-3-PROPYL-3H-IMIDAZOL-4-YL]-PYRIMIDIN-2-YL}AMINE, ... (5 entities in total) |
Functional Keywords | map kinase, apoptosis, inhibition, transferase, transferase-inhibitor complex, transferase/inhibitor |
Biological source | Homo sapiens (Human) |
Cellular location | Cytoplasm : P53779 |
Total number of polymer chains | 1 |
Total formula weight | 43021.34 |
Authors | Scapin, G.,Patel, S.B.,Lisnock, J.,Becker, J.W.,Lograsso, P.V.,Smart, O.S.,Bricogne, G. (deposition date: 2015-04-10, release date: 2015-05-06, Last modification date: 2023-09-27) |
Primary citation | Scapin, G.,Patel, S.B.,Lisnock, J.,Becker, J.W.,LoGrasso, P.V. The structure of JNK3 in complex with small molecule inhibitors: structural basis for potency and selectivity. Chem.Biol., 10:705-712, 2003 Cited by PubMed: 12954329PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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